diff --git a/DOCKER_HUB.md b/DOCKER_HUB.md
index e6fc59e..ac6a804 100644
--- a/DOCKER_HUB.md
+++ b/DOCKER_HUB.md
@@ -184,6 +184,7 @@ Understanding what survives container restarts and what doesn't:
 | `/home/developer/.ssh` | Host bind mount (ro) | ✅ Yes — lives on host | SSH keys |
 | `/home/developer/.aws` | Host bind mount | ✅ Yes — lives on host | AWS credentials/SSO cache |
 | `/home/developer/.local/share/opencode` | Named volume (if configured) | ✅ Yes — Docker volume | Session history, memory, auth tokens |
+| `/home/developer/.local/share/uv` | Named volume (if configured) | ✅ Yes — Docker volume | Python installs, uv tool installs |
 | `/home/developer/.config/opencode` | Host bind mount (if configured) | ✅ Yes — lives on host | opencode.json, oh-my-opencode-slim.json, skills |
 
 ### Key points
@@ -191,6 +192,7 @@ Understanding what survives container restarts and what doesn't:
 - **Project files** (`/workspace`) are always safe — they're your host filesystem.
 - **opencode config** is auto-generated from `OPENCODE_PROVIDER` env var on each start if no existing config is found. To persist config changes, mount the config directory from the host (see Custom opencode Config below).
 - **opencode data** (session history, memory) is lost with `--rm` unless you add a named volume.
+- **Python installs** via `uv python install` are lost unless you add the `devbox-uv` named volume.
 - **AWS SSO tokens** persist across restarts when `~/.aws` is mounted (recommended for Bedrock users).
 
 ## Custom opencode Config
@@ -217,6 +219,39 @@ docker run -it --rm \
   joakimp/opencode-devbox:latest
 ```
 
+## Python Development with uv
+
+The image includes [uv](https://docs.astral.sh/uv/), a fast Python package manager that replaces pip, venv, and pyenv. Python is not pre-installed but can be installed on demand:
+
+```bash
+# Install Python (persists across restarts with devbox-uv volume)
+uv python install 3.12
+
+# Create a virtual environment and install dependencies
+uv venv
+uv pip install -r requirements.txt
+
+# Or use uv's project workflow (reads pyproject.toml)
+uv sync
+
+# Run a Python script
+uv run python script.py
+
+# Install standalone Python tools
+uvx ruff check .
+```
+
+To persist Python installs across container restarts, add a named volume:
+
+```bash
+docker run -it --rm \
+  -v devbox-uv:/home/developer/.local/share/uv \
+  ... \
+  joakimp/opencode-devbox:latest
+```
+
+Project virtual environments (`.venv`) are stored in your workspace directory and persist automatically via the `/workspace` bind mount.
+
 ## Using docker-compose
 
 Create a directory with a `docker-compose.yml` and a `.env` file:
@@ -254,6 +289,8 @@ services:
       - ~/projects:/workspace
       - ~/.ssh:/home/developer/.ssh:ro
       - devbox-data:/home/developer/.local/share/opencode
+      # Optional: persist Python/uv installs across restarts
+      # - devbox-uv:/home/developer/.local/share/uv
       # Mount AWS config for Bedrock SSO (required for amazon-bedrock provider)
       # - ~/.aws:/home/developer/.aws
       # Optional: mount opencode config directory (persists config changes across restarts)
@@ -265,6 +302,7 @@ services:
 
 volumes:
   devbox-data:
+  # devbox-uv:
 ```
 
 Docker Compose loads `.env` automatically from the same directory. All variables from `.env` are passed to the container via `env_file`. Do **not** hardcode provider settings in the `environment:` section — use `.env` instead.
@@ -298,7 +336,7 @@ docker compose run --rm devbox bash   # interactive shell
 - **opencode** — AI coding assistant
 - **Node.js 22** — for npx-based MCP servers
 - **AWS CLI v2** — SSO and Bedrock authentication
-- **Dev tools** — git, git-lfs, ssh, ripgrep, fd, fzf, bat, eza, zoxide, jq, make, curl, wget, neovim 0.12, tmux, htop, tree
+- **Dev tools** — git, git-lfs, ssh, ripgrep, fd, fzf, bat, eza, zoxide, uv, jq, make, curl, wget, neovim 0.12, tmux, htop, tree
 - **Non-root user** — runs as `developer` with UID auto-matched to workspace owner (sudo available)
 
 ### OMOS image (`latest-omos`)
diff --git a/Dockerfile b/Dockerfile
index 456f958..6299814 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -90,6 +90,15 @@ RUN ARCH=$(case "${TARGETARCH}" in amd64) echo "x86_64" ;; arm64) echo "aarch64"
     curl -fsSL "https://github.com/ajeetdsouza/zoxide/releases/download/v${ZOXIDE_VERSION}/zoxide-${ZOXIDE_VERSION}-${ARCH}-unknown-linux-musl.tar.gz" | tar -xz -C /usr/local/bin zoxide && \
     zoxide --version
 
+# uv — fast Python package manager (replaces pip, venv, pyenv)
+ARG UV_VERSION=0.11.6
+RUN ARCH=$(case "${TARGETARCH}" in amd64) echo "x86_64" ;; arm64) echo "aarch64" ;; *) echo "x86_64" ;; esac) && \
+    curl -fsSL "https://github.com/astral-sh/uv/releases/download/${UV_VERSION}/uv-${ARCH}-unknown-linux-musl.tar.gz" | tar -xz -C /tmp && \
+    install /tmp/uv-${ARCH}-unknown-linux-musl/uv /usr/local/bin/uv && \
+    install /tmp/uv-${ARCH}-unknown-linux-musl/uvx /usr/local/bin/uvx && \
+    rm -rf /tmp/uv-* && \
+    uv --version
+
 # Set locale
 RUN sed -i '/en_US.UTF-8/s/^# //g' /etc/locale.gen && locale-gen
 ENV LANG=en_US.UTF-8
diff --git a/README.md b/README.md
index a418615..de76d6f 100644
--- a/README.md
+++ b/README.md
@@ -33,7 +33,8 @@ docker compose run --rm devbox
 - **SSH key forwarding** — git push/pull to private repos
 - **MCP server support** — Node.js included for `npx`-based MCP servers
 - **Non-root user** — runs as `developer` with UID auto-matched to workspace owner (sudo available)
-- **Optional runtimes** — Python, Go via build args (Node.js always included — required for opencode v1.x)
+- **Python via uv** — `uv` package manager included; install Python on demand with `uv python install`
+- **Optional runtimes** — Python (apt), Go via build args (Node.js always included — required for opencode v1.x)
 - **Multi-agent orchestration** — optional [oh-my-opencode-slim](https://github.com/alvinunreal/oh-my-opencode-slim) integration via build arg
 - **AWS CLI v2** — built-in SSO/Bedrock authentication with headless device-code flow
 - **Multi-arch** — amd64 and arm64
@@ -137,6 +138,40 @@ volumes:
   - ~/.config/nvim:/home/developer/.config/nvim:ro
 ```
 
+### Python development with uv
+
+The image includes [uv](https://docs.astral.sh/uv/), a fast Python package manager that replaces pip, venv, and pyenv. Python is not pre-installed but can be installed on demand:
+
+```bash
+# Install Python (persists across restarts with devbox-uv volume)
+uv python install 3.12
+
+# Create a virtual environment and install dependencies
+uv venv
+uv pip install -r requirements.txt
+
+# Or use uv's project workflow (reads pyproject.toml)
+uv sync
+
+# Run a Python script
+uv run python script.py
+
+# Install standalone Python tools
+uvx ruff check .
+```
+
+Python installations are stored in `~/.local/share/uv/`. To persist them across container restarts, add the `devbox-uv` named volume to your `docker-compose.yml`:
+
+```yaml
+volumes:
+  - devbox-uv:/home/developer/.local/share/uv
+
+volumes:
+  devbox-uv:
+```
+
+Project virtual environments (`.venv`) are stored in your workspace directory and persist automatically via the `/workspace` bind mount.
+
 ### Rebuilding the Image
 
 `docker compose run` and `docker compose up` use the existing image — they **do not rebuild** when you change the Dockerfile or build args (e.g. updating `OPENCODE_VERSION`). Rebuild explicitly:
@@ -310,7 +345,7 @@ Container (Debian bookworm)
 ├── opencode binary
 ├── oh-my-opencode-slim (optional — multi-agent orchestration plugin, includes Bun)
 ├── AWS CLI v2 (SSO + Bedrock auth)
-├── neovim 0.12, tmux, htop, bat, eza, zoxide, make
+├── neovim 0.12, tmux, htop, bat, eza, zoxide, uv, make
 ├── git, ssh, ripgrep, fd, fzf, jq, curl, tree
 ├── Node.js (for MCP servers)
 ├── Bun (optional — included with oh-my-opencode-slim)
@@ -326,6 +361,7 @@ Container (Debian bookworm)
 | `/home/developer/.ssh` | Host bind mount (ro) | ✅ Yes | SSH keys |
 | `/home/developer/.aws` | Host bind mount (if configured) | ✅ Yes | AWS credentials/SSO cache |
 | `/home/developer/.local/share/opencode` | Named volume `devbox-data` | ✅ Yes | Session history, memory |
+| `/home/developer/.local/share/uv` | Named volume `devbox-uv` (if configured) | ✅ Yes | Python installs, uv tool installs |
 | `/home/developer/.config/opencode` | Host bind mount (if configured) | ✅ Yes | opencode.json, oh-my-opencode-slim.json, skills |
 
 **opencode config** (`opencode.json`) is auto-generated from `OPENCODE_PROVIDER` on each start. It sets provider and model only — no MCP servers. To persist config changes and use custom settings, mount the config directory from the host (see Custom opencode config above).
diff --git a/docker-compose.yml b/docker-compose.yml
index ca4e9d6..9f518bd 100644
--- a/docker-compose.yml
+++ b/docker-compose.yml
@@ -45,8 +45,13 @@ services:
       # Optional: persist opencode data (auth, memory, etc.)
       - devbox-data:/home/developer/.local/share/opencode
 
+      # Optional: persist uv data (Python installs, tool installs)
+      # Without this, 'uv python install' must be re-run after container removal.
+      - devbox-uv:/home/developer/.local/share/uv
+
       # Optional: AWS credentials/SSO config (not read-only — SSO writes token cache)
       # - ~/.aws:/home/developer/.aws
 
 volumes:
   devbox-data:
+  devbox-uv: